NCT04520672

Circulating Tumor Cells (CTC) in Cancer

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 3,000 (estimated)
• Sponsor: University Hospital, Basel, Switzerland · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This observational study with circulating tumor cells (CTC) count, isolation and analysis at several time points during disease progression is to investigate the role and biology of CTCs and clusters of CTCs in different cancer types. It also evaluates the role of CTCs as biomarkers, and aims at the identification of key signaling networks that are active in CTCs.

Conditions

• Cancer

Interventions

Type	Name	Description
OTHER	Blood samples	Blood samples (3 ethylenediaminetetraacetic acid (EDTA) tubes with a volume of 7.5 ml blood each) will be processed for CTC isolation and characterization, ranging from molecular analysis to culture and drug screen.
OTHER	Samples from tumor draining vessels	In case of tumor resection, 3 EDTA tubes (5 ml) will be withdrawn from the tumor draining vessels for CTC isolation and characterization, ranging from molecular analysis to culture and drug screen.

Timeline

• Start date: 2020-10-01
• Primary completion: 2030-08-01
• Completion: 2030-08-01
• First posted: 2020-08-20
• Last updated: 2025-03-12

Locations

2 sites across 1 country: Switzerland