Clinical Trials Directory

Trials / Terminated

TerminatedNCT04517864

PLACEBO-CONTROLLED SAFETY STUDY OF RITLECITINIB (PF-06651600) IN ADULTS WITH ALOPECIA AREATA

A PHASE 2a, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY INVESTIGATING THE SAFETY OF RITLECITINIB (PF-06651600) IN ADULT PARTICIPANTS WITH ALOPECIA AREATA

Status
Terminated
Phase
Phase 2
Study type
Interventional
Enrollment
71 (actual)
Sponsor
Pfizer · Industry
Sex
All
Age
18 Years – 50 Years
Healthy volunteers
Not accepted

Summary

This is a global Phase 2a randomized, double-blind, placebo-controlled study to evaluate the safety and tolerability of ritlecitinib in adults aged 18 to ≤50 years of age with ≥25% scalp hair loss due to Alopecia Areata (AA).

Conditions

Interventions

TypeNameDescription
DRUGPF-0665160050 mg tablet, dosed as 200 mg QD or 50 mg QD 50 mg capsule, dosed as 50 mg QD
DRUGPlacebotablet, dosed as 4 tablets QD or 1 tablet QD

Timeline

Start date
2020-09-15
Primary completion
2022-01-04
Completion
2024-05-07
First posted
2020-08-18
Last updated
2025-07-11
Results posted
2022-12-28

Locations

38 sites across 4 countries: United States, Australia, Canada, Poland

Regulatory

Source: ClinicalTrials.gov record NCT04517864. Inclusion in this directory is not an endorsement.

PLACEBO-CONTROLLED SAFETY STUDY OF RITLECITINIB (PF-06651600) IN ADULTS WITH ALOPECIA AREATA (NCT04517864) · Clinical Trials Directory