NCT04516525

The Impact of CRT on Renal Function

Assessment of the Impact of Resynchronization Therapy on Renal Function

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 74 (actual)
• Sponsor: University of Rzeszow · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: —

Summary

The study is observational, prospective, including patients undergoing CRT-D / CRT-P implantation in the department of cardiology. In the current project, the researchers assumed that the improvement in cardiac function obtained in patients qualified according to the ESC / PTK guidelines for resynchronization therapy may improve renal function in a prospective 12-month follow-up. In addition, it is planned to take into account the possibility of temporary deterioration of kidney function, which may occur immediately after implantation of the resynchronization device due to the nephrotoxic effect of the contrast agent.

Conditions

• Chronic Kidney Diseases
• Chronic Heart Failure

Interventions

Type	Name	Description
DEVICE	cardiac resynchronisation therapy (CRT) implantation	In a group of 100 patients with chronic cardio-renal syndrome, the blood and urine biomarkers are tested before CRT implantation and after 48 hours, 3 months and 1 year of follow-up.

Timeline

• Start date: 2016-04-15
• Primary completion: 2018-12-15
• Completion: 2020-08-06
• First posted: 2020-08-18
• Last updated: 2020-08-18

Regulatory

• FDA-regulated device study