Trials / Unknown
UnknownNCT04516174
Effect of Transversus Abdominis Plane Block Combined With Dexmedetomidine Infusion on the Prognosis in Elderly Patients Undergoing Abdominal Surgery
- Status
- Unknown
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 180 (estimated)
- Sponsor
- Beijing Tiantan Hospital · Academic / Other
- Sex
- All
- Age
- 65 Years – 80 Years
- Healthy volunteers
- Not accepted
Summary
To compare the prognosis of elderly patients undergoing radical resection of colorectal cancer treated with general anesthesia and general anesthesia combined with transversus abdominis plane block and continuous infusion of dexmedetomidine. The incidence of postoperative delirium, postoperative acute pain moderately to severely and poor postoperative recovery were composite endpoints to determine the prognosis of patients.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Transversus abdominis plane block using ropivacaine | Before anesthesia, the ultrasound-guided bilateral transversus abdominis plane block using 0.25% ropivacaine was perdormed by anesthesiologist who is not involved in intraoperative management and postoperative follow-up and evaluate the effect after the block completed. |
| DRUG | Dexmedetomidine | After finished the transversus abdominis plane block, then perform tracheal intubation and start the infusion of dexmedetomidine. |
| PROCEDURE | Transversus abdominis plane block using saline | Before anesthesia, the ultrasound-guided bilateral transversus abdominis plane block using saline was perdormed by anesthesiologist who is not involved in intraoperative management and postoperative follow-up and evaluate the effect after the block completed. |
| DRUG | Saline | After finished the transversus abdominis plane block, then perform tracheal intubation and start the infusion of saline, dosage and infusion method of saline are consistent with dexmedetomidine. |
Timeline
- Start date
- 2020-09-01
- Primary completion
- 2022-12-31
- Completion
- 2023-09-01
- First posted
- 2020-08-18
- Last updated
- 2020-08-18
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT04516174. Inclusion in this directory is not an endorsement.