NCT04513834

Efficacy of a Multi-faceted Intervention Combining an Educational Outreach Visit to General Practitioners and Patient Education Material to Deprescribe Proton Pump Inhibitors (PPI): a Population-based, Pragmatic, Cluster-randomized Controlled Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 25,000 (actual)
• Sponsor: Nantes University Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Deprescribing is defined as "the process of withdrawal of an inappropriate medication, supervised by a health care professional with the goal of managing the polypharmacy and improving outcomes". Inappropriate use of proton pump inhibitors (PPI) is associated with severe adverse drug reactions and a major economic impact. Deprescribing should be considered when inappropriate prescription of PPI is identified. DeprescrIPP DAM is a pragmatic trial, population-based, designed in clusters. It wil assess the efficacy of a multi-faceted intervention (an educational outreach visit to general practitioners associated with the sending of patient education material to their patients) to deprescribe PPI.

Conditions

• Proton Pump Inhibitors
• Deprescription

Interventions

Type	Name	Description
OTHER	GP will receive the educational outreach visit by a DAM (healthcare representative).	GP will receive the educational outreach visit by a DAM (healthcare representative).
OTHER	Patient education material on PPI deprescribing will be sent to the patients	Patient education material on PPI deprescribing will be sent to the patients

Timeline

• Start date: 2022-09-19
• Primary completion: 2023-09-19
• Completion: 2023-12-19
• First posted: 2020-08-14
• Last updated: 2024-04-22

Locations

1 site across 1 country: France