Clinical Trials Directory

Trials / Completed

CompletedNCT04513249

Effects of Therapeutic Plasmaexhange on Viscoelastic Tests in Non-coagulopathic Patients

Status
Completed
Phase
Study type
Observational
Enrollment
25 (actual)
Sponsor
Institutul Clinic Fundeni · Academic / Other
Sex
All
Age
18 Minutes
Healthy volunteers
Not accepted

Summary

Therapeutic plasma exchange is widely performed in patients with autoimmune disease. The exact effects of fresh frozen plasma on coagulation in this group of patients remains unknown. In order to investigate this issue the present study monitors periprocedural coagulation status with the aid of standard coagulation tests and rotational thromboelastometry. Four thromboelastometric tests will be performed: ExTEM, InTEM, FibTEM and ApTEM. The following parameters will be recorded from each test: CT (sec), CFT (sec) and MCF (mm) one hour before and one hour after plasmaechange was performed.

Conditions

Interventions

TypeNameDescription
DIAGNOSTIC_TESTdynamics of coagulation parametersthe effects of fresh frozen plasma administered during a plasma exchange therapy on viscoelastic tests

Timeline

Start date
2017-05-10
Primary completion
2017-12-30
Completion
2017-12-30
First posted
2020-08-14
Last updated
2020-08-14

Locations

1 site across 1 country: Romania

Source: ClinicalTrials.gov record NCT04513249. Inclusion in this directory is not an endorsement.