NCT04508634

Treating Obese PCOS Patients With LSG vs. Met

Comparison of the Clinical Efficacy of Laparoscopic Sleeve Gastrectomy and Metformin in the Treatment of Obese Patients With Polycystic Ovary Syndrome

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 90 (estimated)
• Sponsor: Shanghai 10th People's Hospital · Academic / Other
• Sex: Female
• Age: 18 Years – 45 Years
• Healthy volunteers: Not accepted

Summary

Polycystic ovary syndrome (PCOS) is a common endocrine disorder, with a prevalence of 5% to 15% in premenopausal women. Patients with PCOS presents as abnormal menstruation, ovulation disorders and/or hyperandrogenemia, and often accompanied by insulin resistance and other metabolic abnormalities. Sleeve gastrectomy was an effective threapy for severe obesity patients. This study will evaluate the clinical efficacy of sleeve gastrectomy for obese patients with PCOS. Mealwhile, the specific mechanism of sleeve gastrectomy for improving obese patients with PCOS will be explored through multi-group analysis.

Conditions

• Polycystic Ovary Syndrome

Interventions

Type	Name	Description
PROCEDURE	laparoscopic sleeve gastrectomy	laparoscopic sleeve gastrectomy
DRUG	Metformin Pill	Metformin 1000mg bid

Timeline

• Start date: 2020-11-01
• Primary completion: 2024-09-01
• Completion: 2024-09-30
• First posted: 2020-08-11
• Last updated: 2023-04-12

Locations

1 site across 1 country: China