NCT04503889

The Effect of Transauricular Electrical Vagal Nerve Stimulation on Temporal Summation of Pain in Patients With Back Pain

The Effect of Transauricular Electrical Vagal Nerve Stimulation on Temporal Summation of Heat Pain in Patients With Chronic Low-back Pain

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: University Medicine Greifswald · Academic / Other
• Sex: All
• Age: 30 Years – 60 Years
• Healthy volunteers: Accepted

Summary

The effect of transauricular electrical vagal nerve stimulation (taVNS) will be studied on temporal summation of heat pain (TSP) in 30 patients with chronic low-back pain and in 30 heathy volunteers. Participants will receive either taVNS or sham stimulation before and during TSP induction in a randomized crossover manner. The participants will be unaware regarding the type of intervention.

Conditions

• Pain Intensity

Interventions

Type	Name	Description
DEVICE	Transauricular electrical vagal nerve stimulation	transauricular electrical vagal nerve stimulation will be applied to the cymba conchae of both ears using ECO2 TENS device (manufactured by Schwa-Medico GmbH/Germany) with currency intensity of max 10 mA and current frequency 2/100 Hz.
DEVICE	taVNS sham	ECO2 TENS device (manufactured by Schwa-Medico GmbH/Germany)

Timeline

• Start date: 2019-01-23
• Primary completion: 2021-12-01
• Completion: 2021-12-01
• First posted: 2020-08-07
• Last updated: 2020-08-07

Locations

1 site across 1 country: Germany