NCT04502290

Synchronized Brain and Hand Stimulation After Stroke

Synchronized Brain and Hand Stimulation to Improve Hand Function After Stroke

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 10 (actual)
• Sponsor: Amit Sethi · Academic / Other
• Sex: All
• Age: 18 Years – 85 Years
• Healthy volunteers: Not accepted

Summary

Among the 795,000 individuals who sustain a stroke annually in the United States, 65% continue to experience moderate-to-severe impairments in one hand six months or more, which limits their ability to perform daily tasks. Currently there is dearth of understanding of the mechanisms of motor recovery after stroke. Understanding the mechanisms can potentially lead to the development of interventions to improve motor performance after stroke. The proposed study will examine how synchronously pairing brain and hand stimulation repeatedly affects the plasticity of the brain and motor performance after stroke. The knowledge gained from this study can be useful to develop interventions to improve hand movement after moderate-severe stroke.

Conditions

• Stroke
• Upper Extremity Paresis

Interventions

Type	Name	Description
DEVICE	Combined Non-invasive brain stimulation and functional electrical hand stimulation	Participants will receive synchronously combined non-invasive brain stimulation (delivered via electrical/magnetic stimulation) with functional electrical stimulation (delivered via DS7A or Neuromove) of the weak hand

Timeline

• Start date: 2020-10-01
• Primary completion: 2024-05-22
• Completion: 2024-05-22
• First posted: 2020-08-06
• Last updated: 2025-07-15
• Results posted: 2025-07-15

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated device study