Trials / Unknown
UnknownNCT04500002
Isonicotinic Acid Hydrazide (INH) Pretreatment With Misoprostol Versus Misoprostol Alone in Missed Abortion
Adjuvant Isonicotinic Acid Hydrazide (INH) Pretreatment With Misoprostol for Induction of Abortion in First-trimester Missed Miscarriage: A Randomized Controlled Trial
- Status
- Unknown
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 240 (estimated)
- Sponsor
- Aswan University Hospital · Academic / Other
- Sex
- Female
- Age
- 18 Years – 45 Years
- Healthy volunteers
- Not accepted
Summary
The primary endpoint was the success rate of adjuvant isonicotinic acid hydrazide (INH) and misoprostol versus misoprostol alone for medical termination of first-trimester pregnancy.
Detailed description
According to the American college of obstetricians and gynecologists (2005), medical abortion is an acceptable alternative for surgical procedures in pregnant women with gestational age of less than 10 weeks based on the last menstrual period Oral or vaginal misoprostol causes complete abortion in almost 85% of cases within seven days before the 12th week Adjuvant isonicotinic acid hydrazide (INH) administration with misoprostol raises the rate of complete abortion
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Isonicotinic Acid Hydrazide | total dose 900 mg per day for 3 days then Misoprosrol 800mcg will be given to all patients for induction of abortion |
| DRUG | Misoprostol | Misoprosrol 800mcg will be given to all patients for induction of abortion |
Timeline
- Start date
- 2020-09-01
- Primary completion
- 2021-06-30
- Completion
- 2021-07-30
- First posted
- 2020-08-05
- Last updated
- 2020-08-05
Locations
1 site across 1 country: Egypt
Source: ClinicalTrials.gov record NCT04500002. Inclusion in this directory is not an endorsement.