Trials / Completed
CompletedNCT04497766
Comparasion of Efficacy of Nebulized With Intravenous Magnesium Sulphate in Children With Asthma
Comparasion of Efficacy of Nebulized Magnesium Sulphate With Intravenous Magnesium Sulphate in Children With Acute Asthma
- Status
- Completed
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 148 (actual)
- Sponsor
- Saima Khatoon · Academic / Other
- Sex
- All
- Age
- 2 Years – 12 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of study is to assess the effectiveness of nebulized magnesium sulphate in children presenting with acute asthma.Study perfoma consists of demographic variables,exclusion criteria and pediatric asthma score that includes respiratory rate,SPO2 at room air(requirement of oxygen),auscultatory findings in chest,dysnea and retractions.
Detailed description
After getting informed consent from guardian,148 patients of acute moderate ro severe asthma with pediatric asthma score 8-15 will be randomly classified into 2 groups and one group will receive nebulization with magnesium sulphate and other will receive intravenous magnesium sulphate and effectiveness will be compared by 4 point reduction in PAS from baseline in either groups after 6 hours.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Nebulized Magnesium sulfate | MgSO4 100mg in 20 ml normal saline will be given via ultrasonic nebulizer over 10 minutes,and PAS score will be assessed at 30,60,120,240,360 minutes |
| DRUG | Intravenous magnesium sulphate | pts age 2 to 12 years will receive intravenous magnesium sulphate 50 mg/kg over half hour |
Timeline
- Start date
- 2019-10-01
- Primary completion
- 2020-09-30
- Completion
- 2020-09-30
- First posted
- 2020-08-04
- Last updated
- 2021-02-23
Locations
1 site across 1 country: Pakistan
Source: ClinicalTrials.gov record NCT04497766. Inclusion in this directory is not an endorsement.