Trials / Completed
CompletedNCT04494659
A Drug-drug Interaction Trial to Evaluate the Pharmacokinetics Effect of Rifampicin on Famitinib
A Single Center, Single Arm, Open and Fixed Sequence Study to Investigate the Pharmacokinetic Effects of Rifampicin on Famitinib in Healthy Male Subjects
- Status
- Completed
- Phase
- Phase 1
- Study type
- Interventional
- Enrollment
- 21 (actual)
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd. · Industry
- Sex
- Male
- Age
- 18 Years – 50 Years
- Healthy volunteers
- Accepted
Summary
The primary objective of the study was to assess the effect of repeated oral doses of Rifampicin on the pharmacokinetic profile of a single dose of Famitinib. The secondary objective of the study was to assess the safety of Famitinib given alone versus Famitinib co-administered with Rifampicin.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Famitinib capsule | single dose and co-administrated with Rifampicin capsule |
| DRUG | Rifampicin capsule | repeated doses of Rifampicin capsule |
Timeline
- Start date
- 2020-07-20
- Primary completion
- 2020-08-13
- Completion
- 2020-08-31
- First posted
- 2020-07-31
- Last updated
- 2020-09-29
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT04494659. Inclusion in this directory is not an endorsement.