NCT04493554

The Effects of Vasopressin on Attention Control

The Effects of Vasopressin on Attention Control: An Eye-tracking Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 89 (actual)
• Sponsor: University of Electronic Science and Technology of China · Academic / Other
• Sex: Male
• Age: 18 Years – 30 Years
• Healthy volunteers: Accepted

Summary

The main aim of the present study is to investigate whether intranasal vasopressin (20IU) could influence attention control in a social-emotional saccade/antisaccade eye-tracking paradigm.

Detailed description

A number of previous studies have reported vasopressin's effect on human social behavior and social cognition, although it remains unclear whether vasopressin could modulate attention allocation including stimulus-driven bottom-up control and goal-directed top-down control. In the current randomized, between-subject, placebo controlled study, 89 healthy male subjects will be recruited and receive either vasopressin (20 IU) or placebo control administered intranasally. 45 minutes after treatment subjects will be required to complete a social-emotional saccade /antisaccade eye-tracking paradigm. The paradigm uses social (happy, sad, angry, fear, and neutral faces) as well as non-social (oval shapes) stimuli to explore social- and emotion-specific effects of vasopressin.

Conditions

• Healthy

Interventions

Type	Name	Description
DRUG	Vasopressin	Administration of vasopressin (20 IU) intranasally
DRUG	Placebo	Administration of placebo intranasally

Timeline

• Start date: 2020-07-28
• Primary completion: 2020-11-30
• Completion: 2021-01-01
• First posted: 2020-07-30
• Last updated: 2021-01-07

Locations

1 site across 1 country: China