NCT04492969

Prospective Observation of Failure Patterns in NSCLC Treated With ICIs

Prospective Observational Study of Failure Patterns in Non-small Cell Lung Cancer Patients Treated With Immune Checkpoint Inhibitors

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 320 (estimated)
• Sponsor: Fudan University · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: —

Summary

By prospectively observing the time to the best therapeutic effect of non-small cell lung cancer after ICI treatment, the characteristics of lesion distribution when the best therapeutic effect is reached, and the phenotype of disease progression after ICI treatment response, the investigators intended to explore the failure pattern of NSCLC after the once effective ICI treatment. The investigators also aim to evaluate the feasibility and clinical value of radiotherapy for the treatment of oligo-progressive lesions after ICI.

Conditions

• NSCLC Stage IV
• NSCLC, Recurrent

Timeline

• Start date: 2020-09-01
• Primary completion: 2023-08-31
• Completion: 2025-08-31
• First posted: 2020-07-30
• Last updated: 2020-07-31

Locations

1 site across 1 country: China