NCT04492319

Addition of Neostigmine to Levobupivacaine

The Effect of Addition of Neostigmine to Levobupivacaine in Male Patients Receiving Ultrasound Guided Spermatic Cord Block for Postoperative Analgesia in Testicular Sperm Extraction Surgery:

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 112 (actual)
• Sponsor: Cairo University · Academic / Other
• Sex: Male
• Age: 20 Years – 60 Years
• Healthy volunteers: Accepted

Summary

Using the spermatic cord block has been of great advantage, as it has been cost saving, efficient technique whether used inon its own or combination with a sedative or . Furthermore, it provides minimal cardiac risks, early case ambulation, satisfactory postoperative pain control, as well as a reduced hospital stay and cost. one of the major drawbacks of spermatic cord block is being a single injection technique, leading to a short postoperative analgesia duration. So, to overcome this flaw some adjuvants were proven to prolong the analgesia duration as neostigmine.

Conditions

• Spermatic Cord Block

Interventions

Type	Name	Description
DRUG	Control Test	spermatic cord block by 19 ml Levobupivacaine 0.5% plus 1 ml 0.9 normal saline in each side
DRUG	Neostigmine	spermatic cord block by 19 ml Levobupivacaine 0.5% plus 1 ml neostigmine 500 μg in each side .

Timeline

• Start date: 2020-09-29
• Primary completion: 2023-11-23
• Completion: 2023-12-20
• First posted: 2020-07-30
• Last updated: 2024-01-09

Locations

1 site across 1 country: Egypt