Clinical Trials Directory

Trials / Completed

CompletedNCT04490499

A Hepatitis B Vaccine Challenge Study After Previous Vaxelis® Vaccination (V419-013)

A Hepatitis B Vaccine Challenge Study to Demonstrate the Durability of Protection Against Hepatitis B Virus Infection in Healthy Children Vaccinated Approximately 9 Years Previously With a 2- or 3-Dose Infant Series and Toddler Dose of Vaxelis®

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
207 (actual)
Sponsor
Merck Sharp & Dohme LLC · Industry
Sex
All
Age
8 Years – 10 Years
Healthy volunteers
Accepted

Summary

The purpose of this study is to demonstrate the durability of protection against hepatitis B virus (HBV) infection approximately 8-9 years after vaccination with Vaxelis®. This is an estimation study, and no formal hypothesis testing was performed.

Conditions

Interventions

TypeNameDescription
BIOLOGICALHBVAXPRO™Single 0.5 mL intramuscular dose

Timeline

Start date
2020-09-02
Primary completion
2020-12-29
Completion
2020-12-29
First posted
2020-07-29
Last updated
2022-07-27
Results posted
2021-09-05

Locations

10 sites across 1 country: Finland

Regulatory

Source: ClinicalTrials.gov record NCT04490499. Inclusion in this directory is not an endorsement.