Trials / Recruiting
RecruitingNCT04487925
Controlled Ovarian Stimulation Versus Modified Natural Cycles in Poor Responders
A Randomized Comparison of One Controlled Ovarian Stimulation With Corifollitropin Alfa Versus up to Three Modified Natural Cycles in Expected and Established Poor Responders
- Status
- Recruiting
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 208 (estimated)
- Sponsor
- University Hospital, Ghent · Academic / Other
- Sex
- Female
- Age
- 18 Years – 44 Years
- Healthy volunteers
- Not accepted
Summary
This is a prospective, randomized, single center, phase 4 controlled trial. The study will compare the efficacy of two different strategies for the management of predicted poor response patients under stimulation for IVF/ICSI: up to three MNC cycles (group 1) versus a single GnRH antagonist CFA (group 2).
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | A single Gonadotropin-Releasing Hormone (GnRH) antagonist corifollitropin alfa (CFA) stimulation | CFA will be administered in combination with Follitropin beta. |
| DRUG | Up to three modified natural cycles with Follitropin beta. | Follitropin beta in a low dose will be given. |
Timeline
- Start date
- 2022-01-25
- Primary completion
- 2024-09-30
- Completion
- 2024-12-31
- First posted
- 2020-07-27
- Last updated
- 2024-05-09
Locations
1 site across 1 country: Belgium
Source: ClinicalTrials.gov record NCT04487925. Inclusion in this directory is not an endorsement.