Trials / Recruiting
RecruitingNCT04487041
Tfh Dysfunction in HIV and Aging
- Status
- Recruiting
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 400 (estimated)
- Sponsor
- University of Miami · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Accepted
Summary
The purpose of this research is to evaluate blood samples from HIV infected and non-HIV infected people to understand how aging and HIV infection affect the immune responses (body defenses against infection) to the flu vaccine.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| BIOLOGICAL | Standard dose influenza vaccination | Single 0.5 ml injection administered intramuscularly into participant's deltoid muscle |
| BIOLOGICAL | High dose influenza vaccination | 4 times more concentrated single 0.7 ml injection administered intramuscularly into participant's deltoid muscle |
Timeline
- Start date
- 2020-10-30
- Primary completion
- 2026-06-30
- Completion
- 2026-12-30
- First posted
- 2020-07-27
- Last updated
- 2025-05-30
Locations
1 site across 1 country: United States
Regulatory
- FDA-regulated drug study
Source: ClinicalTrials.gov record NCT04487041. Inclusion in this directory is not an endorsement.