Clinical Trials Directory

Trials / Suspended

SuspendedNCT04485065

Safety and Efficacy of IBI188 With Azacitidine in Subjects With Newly Diagnosed Higher Risk MDS

A Phase Ib Study Evaluating the Safety and Efficacy of IBI188 in Combination With Azacitidine in Subjects With Newly Diagnosed Higher Risk Myelodysplastic Syndrome

Status
Suspended
Phase
Phase 1
Study type
Interventional
Enrollment
120 (estimated)
Sponsor
Innovent Biologics (Suzhou) Co. Ltd. · Industry
Sex
All
Age
18 Years – 99 Years
Healthy volunteers
Not accepted

Summary

The study is to evaluate safety and efficacy of IBI188 in combination with azacitidine (AZA) as a first-line treatment in subjects with newly diagnosed higher risk myelodysplastic syndrome

Conditions

Interventions

TypeNameDescription
DRUGIBI188+azacitidineEscalating and maintenance dose of IBI188 will be administered 30mg/kg, IV(intravenous infusion),Q4W Drug:Azacitidine Azacitidine will be administered daily for 7 days, IH, Q4W

Timeline

Start date
2020-09-30
Primary completion
2023-12-30
Completion
2024-08-20
First posted
2020-07-24
Last updated
2023-02-16

Locations

1 site across 1 country: China

Source: ClinicalTrials.gov record NCT04485065. Inclusion in this directory is not an endorsement.