NCT04483921

SubsTRate OxidatioN in Girls

Race Differences in 24-hour Energy Expenditure, Substrate Oxidation, and Appetite in Adolescent Girls

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 14 (actual)
• Sponsor: Pennington Biomedical Research Center · Academic / Other
• Sex: Female
• Age: 13 Years – 17 Years
• Healthy volunteers: Accepted

Summary

This study will examine race differences in total energy expenditure and respiratory quotient (RQ) during and after exercise, compared to a sedentary control condition, in adolescent girls who are classified as overweight. In addition, subjective appetite and objective energy intake will be measured throughout the assessment periods.

Detailed description

Aim 1: Measure 24-hour energy expenditure and its components (resting, activity, and sleep energy expenditure) and compare differences between African-American and White girls. Hypothesis: Total, resting, and sleep energy expenditure will be lower in African-American relative to White girls. Activity energy expenditure will be equivalent per the study design. Aim 2: Measure and compare substrate oxidation and associations with appetite (i.e., hunger, desire to eat) and energy intake between African-American and White girls. Hypothesis: African-American girls will have a higher RQ at rest, during exercise, and following exercise, and RQ will be positively associated with subjective appetite ratings and energy intake.

Conditions

• Overweight Adolescents

Interventions

Type	Name	Description
OTHER	Acute exercise	Participants will complete a morning exercise bout at 70% of their individual maximal aerobic capacity to burn 200 kilocalories above their basal metabolic rate.

Timeline

• Start date: 2020-07-15
• Primary completion: 2023-09-02
• Completion: 2023-10-20
• First posted: 2020-07-23
• Last updated: 2024-04-02

Locations

1 site across 1 country: United States