NCT04482985

Meclizine Plasma Levels in Responders and Non-responders

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 50 (estimated)
• Sponsor: Medical Corps, Israel Defense Force · Academic / Other
• Sex: All
• Age: 18 Years – 40 Years
• Healthy volunteers: Accepted

Summary

Motion sickness is a debilitating condition that can effect many crew members. Meclizine has long been known as an effective anti motion sickness drug. The response to the drug is variable - some are responders, while others are resistant to the drug. The aim of the present study is to examine whether there is a correlation between meclizine plasma levels and clinical response.

Conditions

• Seasickness
• Meclizine

Interventions

Type	Name	Description
DRUG	Meclizine Hydrochloride	Meclzine is given to all study participants to prevent seasickness. Meclizine plasma levels are determined from both the meclizine responders and non responders group.

Timeline

• Start date: 2020-09-01
• Primary completion: 2021-09-01
• Completion: 2021-09-01
• First posted: 2020-07-23
• Last updated: 2020-07-23

Regulatory

• FDA-regulated drug study