NCT04481997

Anti-thrombotic and Glucose Lowering Therapy in Diabetic Patients Undergoing PCI

Anti-thrombotic and Glucose loweRing THerapy in diabEtics With CAD Undergoing PCI: a Prospective Multicenter observatIonal Study on Their Use and Implications for Clinical Outcomes - The ARTHEMIS Registry

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 1,000 (actual)
• Sponsor: Associacao para Investigacao e Desenvolvimento da Faculdade de Medicina - CETERA · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Diabetes mellitus (DM) is one of the main risk factors for ischemic events in patients with coronary artery disease (CAD) and diabetes is a factor in several post-PCI (Percutaneous Coronary Intervention) risk scores. However, until recently, there were almost no studies performed specifically in the diabetic population of patients undergoing PCI. This study aims to describe the anti-thrombotic regimens, clinical outcomes and current diabetes medical treatment in an unselected consecutive population of patients with DM undergoing PCI.

Detailed description

Diabetes is one of the main risk factors for ischemic events in patients with coronary artery disease and diabetes is a factor in several post-PCI risk scores (including the commonly used DAPT score). However, until recently, there were almost no studies performed specifically in the diabetic population of patients undergoing PCI. At large, results from randomized trials assessing the duration of DAPT have produced conflicting results and there is uncertainty about the best anti-thrombotic strategy in patients with diabetes. Further assessment of the patterns of use and their clinical effects, including those related to prolonged DAPT is needed, in diabetic patients, especially in less selected "real world" populations.

Conditions

• Type2 Diabetes Mellitus
• Coronary Heart Disease

Interventions

Type	Name	Description
OTHER	Exposure to Anti-thrombotic treatment agents and glucose lowering therapy	Exposure to Anti-thrombotic treatment agents and glucose lowering therapy

Timeline

• Start date: 2021-01-11
• Primary completion: 2023-11-04
• Completion: 2024-01-30
• First posted: 2020-07-22
• Last updated: 2025-08-29

Locations

12 sites across 1 country: Portugal