Trials / Completed
CompletedNCT04481789
Clinical Pharmacology Study of Oral Edaravone in Healthy Adult Males (Drug Interaction Study and Preliminary Regimen-Finding Study)
- Status
- Completed
- Phase
- Phase 1
- Study type
- Interventional
- Enrollment
- 84 (actual)
- Sponsor
- Tanabe Pharma Corporation · Industry
- Sex
- Male
- Age
- 20 Years – 45 Years
- Healthy volunteers
- Accepted
Summary
* Cohort 1: To evaluate the drug interactions, safety, and tolerability of oral edaravone when coadministered with rosuvastatin, sildenafil or furosemide in healthy adult males * Cohort 2: To evaluate the pharmacokinetics, safety, and tolerability of oral edaravone in healthy Japanese and Caucasian adult males
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | MT-1186 | Suspension |
| DRUG | Rosuvastatin | Tablets |
| DRUG | Sildenafil | Tablets |
| DRUG | Furosemide | Tablets |
Timeline
- Start date
- 2018-10-17
- Primary completion
- 2018-12-20
- Completion
- 2019-01-08
- First posted
- 2020-07-22
- Last updated
- 2026-01-07
- Results posted
- 2024-08-02
Locations
1 site across 1 country: Japan
Source: ClinicalTrials.gov record NCT04481789. Inclusion in this directory is not an endorsement.