NCT04476238

Inosine Energy Expenditure Study

Randomized Cross-over Trial to Investigate the Effect of Inosine on Human Energy Expenditure

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 8 (actual)
• Sponsor: University Hospital, Basel, Switzerland · Academic / Other
• Sex: Male
• Age: 18 Years – 40 Years
• Healthy volunteers: Accepted

Summary

Investigators want to test whether the intake of the nucleoside inosine increases the human energy expenditure. Inosine occurs as a metabolic intermediate in the human body and is sometimes taken as a dietary supplement by athletes. For this purpose, investigators will measure the basal metabolic rate by indirect calorimetry. Study participants will then take inosine dissolved in water or placebo and energy expenditure will be assessed again.

Conditions

• Healthy Volunteers

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Inosine	2 grams of inosine dissolved in 250 ml water taken by mouth
OTHER	Placebo	250 ml water taken by mouth

Timeline

• Start date: 2022-02-28
• Primary completion: 2022-12-31
• Completion: 2023-04-30
• First posted: 2020-07-20
• Last updated: 2023-09-28

Locations

1 site across 1 country: Switzerland