NCT04475237

Virtual Anatomical Reconstruction of Mandibular Bone Defects Using a Statistical Shape Model

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 100 (actual)
• Sponsor: CADskills · Industry
• Sex: All
• Age: 20 Years – 60 Years
• Healthy volunteers: Accepted

Summary

Hundred already taken CT-scans (50 male and 50 female) will be anonymized. These scans will be segmented and implemented into a statistical shape model that will be used to predict missing hard tissue of a mandible based on the remaining bone.

Detailed description

Together with the radiology and Craniomaxillofacial (CMF) department, 100 scans will be selected from the database (50 males and 50 females, between 20 and 60 years old). First, they will be anonymized (except the sex and age/date of birth). Afterwards, they will be segmented using Materialise Mimics software. The segmented mandibles will then be used to create a statistical shape model (SSM) using principal component analysis. This model will afterwards be used to predict the mandibular shapes.

Conditions

• Mandibular Diseases
• SSM

Interventions

Type	Name	Description
OTHER	CT-scan evaluation and segmentation	CT-scans will be evaluated (to see if they are included in the research group) and segmented if they are accepted.

Timeline

• Start date: 2020-01-01
• Primary completion: 2021-05-01
• Completion: 2021-05-05
• First posted: 2020-07-17
• Last updated: 2021-08-03

Locations

1 site across 1 country: Belgium