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Trials / Terminated

TerminatedNCT04472897

A Study to Evaluate Safety, Tolerability and Pharmacokinetics of GSK2556286 in Healthy Adult Participants

A Randomised, Double Blind (Sponsor Unblinded), Placebo-controlled, First Time in Human Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Single and Repeat Oral Doses and the Food Effect of GSK2556286 in Healthy Adult Participants

Status
Terminated
Phase
Phase 1
Study type
Interventional
Enrollment
92 (actual)
Sponsor
GlaxoSmithKline · Industry
Sex
All
Age
18 Years – 60 Years
Healthy volunteers
Accepted

Summary

This first time in human (FTIH) study assesses the safety, tolerability, and pharmacokinetics (PK) of single and multiple increasing doses of GSK2556286. It also includes food effect cohorts to evaluate how food influences the PK of GSK2556286. The findings will help determine appropriate dosing for future clinical studies.

Conditions

Interventions

TypeNameDescription
DRUGGSK2556286GSK2556286 will be administered.
DRUGPlaceboPlacebo will be administered

Timeline

Start date
2020-10-30
Primary completion
2024-11-06
Completion
2024-11-06
First posted
2020-07-16
Last updated
2025-05-11

Locations

2 sites across 2 countries: Netherlands, United Kingdom

Source: ClinicalTrials.gov record NCT04472897. Inclusion in this directory is not an endorsement.

A Study to Evaluate Safety, Tolerability and Pharmacokinetics of GSK2556286 in Healthy Adult Participants (NCT04472897) · Clinical Trials Directory