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UnknownNCT04471688

Multicenter Study on Detection Strategy of Infectious Diseases in Blood Transfusion

Status
Unknown
Phase
Study type
Observational
Enrollment
10,000 (estimated)
Sponsor
The Third Xiangya Hospital of Central South University · Academic / Other
Sex
All
Age
1 Year – 100 Years
Healthy volunteers
Accepted

Summary

In the past ten years, nucleic acid detection technology has overcome the limitations of serological detection, reduced missed detections due to window period, occult infection, etc., and its application in the field of pathogen detection has developed rapidly. Since 2015, domestic blood collection and supply institutions have fully popularized nucleic acid testing. The safety screening of blood sources mostly adopts the method of combining two times of enzyme-free negative and one time of nucleic acid testing, which excludes the guarantee of blood safety to the greatest extent. At present, the clinical pre-transfusion and pre-operative infectious disease screening in our country is still serological detection. The use of nucleic acid detection for infectious disease screening can better realize the significance of patients' pre-transfusion/pre-operative infectious disease screening. Therefore, this study will analyze the nucleic acid detection technology and clinical serological detection technology in order to solve three problems: * Explore the best detection strategy for patients with pre-transfusion/pre-operative infectious disease screening; ② Explore the confirmation process of the gray area results of infectious disease serological testing; ③ Better realize the significance of screening for patients' infectious diseases.

Conditions

Interventions

TypeNameDescription
DIAGNOSTIC_TESTinfectious disease screeningExplore the best detection strategy for patients with pre-transfusion/pre-operative infectious disease screening

Timeline

Start date
2020-06-01
Primary completion
2020-12-01
Completion
2021-12-01
First posted
2020-07-15
Last updated
2020-07-15

Locations

1 site across 1 country: China

Source: ClinicalTrials.gov record NCT04471688. Inclusion in this directory is not an endorsement.