NCT04468698

Intra-Abdominal Pressure Effect on Intra-Abdominal Volume and Airway Pressures During Laparoscopy

Intra-Abdominal Pressure Effect on Intra-Abdominal Volume and Airway Pressures During Pneumoperitoneum Insufflation - a Patient-Level Meta-Analysis of Three Randomized Clinical Trials

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 204 (actual)
• Sponsor: Hospital Universitario La Fe · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

During pneumoperitoneum insufflation the insufflated gas increase intra-abdominal pressure. The generated pressure can lead to a different increase in volume depending on the abdominal cavity and patients' characteristics. The primary objective is to determine the relationship between intraabdominal pressure (IAP) and intraabdominal volume (IAV) during pneumoperitoneum insufflation. The secondary objective is to determine the rate of abdominal-thoracic transmission (ATT) assessing the correlation between IAP and respiratory driving pressure (ΔPRS).

Conditions

• Surgery
• Pneumoperitoneum
• Intra Abdominal Pressure

Interventions

Type	Name	Description
OTHER	Peritoneum insufflation	Before surgery pneumoperitoneum is established by insufflating gas into the abdomen. Intraabdominal pressure (IAP) is set to 15 mmHg for initial abdominal stretching and then decreased in a stepwise manner down until 8 mmHg.

Timeline

• Start date: 2019-01-01
• Primary completion: 2019-12-31
• Completion: 2020-07-01
• First posted: 2020-07-13
• Last updated: 2020-07-16

Locations

1 site across 1 country: Spain