NCT04468230

Study of Nicotine for Pain Associated With Chemotherapy-Induced Peripheral Neuropathy

Phase 2 Study of Nicotine for the Treatment of Pain Associated With Chemotherapy-Induced Peripheral Neuropathy

• Status: Terminated
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 4 (actual)
• Sponsor: Virginia Commonwealth University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Assess the efficacy of short-term nicotine transdermal patch administration for the treatment of chemotherapy-induced peripheral neuropathy (CIPN) in cancer stable patients or patients in remission.

Detailed description

This phase 2 study will test the efficacy of short-term transdermal nicotine transdermal patch administration in patients who have been diagnosed with CIPN. The study will follow an open-label, crossover within-subjects clinical trial design with nicotine transdermal patch.

Conditions

• Neuropathy
• Peripheral Neuropathy
• Neuropathic Pain
• Chemotherapy-induced Peripheral Neuropathy

Interventions

Type	Name	Description
DRUG	Nicotine Transdermal Patch	Nicotine Treatment Condition

Timeline

• Start date: 2020-07-31
• Primary completion: 2022-05-31
• Completion: 2022-05-31
• First posted: 2020-07-13
• Last updated: 2023-11-08
• Results posted: 2023-11-08

Locations

2 sites across 1 country: United States

Regulatory

• FDA-regulated drug study