Clinical Trials Directory

Trials / Withdrawn

WithdrawnNCT04467281

A Study of PET/CT Scans With the Radioactive Tracer 89Zr-DFO-Daratumumab in People With Myeloma

A Diagnostic Study of CD38-Targeted ImmunoPET of Myeloma: Phase 2 Trial of Clinical Applications

Status
Withdrawn
Phase
Phase 2
Study type
Interventional
Enrollment
0 (actual)
Sponsor
Memorial Sloan Kettering Cancer Center · Academic / Other
Sex
All
Age
21 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to see if using the radioactive tracer 89Zr-DFO-daratumumab with PET/CT scans is a practical and effective way to view and monitor multiple myeloma in participants before and during their treatment with daratumumab. We also want to see if 89Zr-DFO-daratumumab PET/CT scans can predict a participant's response to therapy, and if they can better locate any leftover disease following treatment compared to the standard imaging methods.

Conditions

Interventions

TypeNameDescription
DRUG89Zr-DFO-daratumumabPatients will undergo 89Zr-DFO-daratumumab PET/CT once before standard of care therapy and once again afterward, for a total of two research scans.
DIAGNOSTIC_TESTPET/CTPatients will undergo 89Zr-DFO-daratumumab PET/CT once before standard of care therapy and once again afterward, for a total of two research scans.

Timeline

Start date
2020-06-30
Primary completion
2021-02-26
Completion
2021-02-26
First posted
2020-07-13
Last updated
2022-07-01

Regulatory

Source: ClinicalTrials.gov record NCT04467281. Inclusion in this directory is not an endorsement.