Clinical Trials Directory

Trials / Completed

CompletedNCT04464408

Favipiravir Therapy in Adults With Mild COVID-19

A Trial of Favipiravir Therapy in Adults With Mild Coronavirus Disease COVID-19

Status
Completed
Phase
Phase 2 / Phase 3
Study type
Interventional
Enrollment
231 (actual)
Sponsor
King Abdullah International Medical Research Center · Academic / Other
Sex
All
Age
18 Years – 100 Years
Healthy volunteers
Not accepted

Summary

Favipiravir is a selective and potent inhibitor of influenza viral RNA polymerase. It acts as a purine analogue, which selectively inhibits viral RNA-dependent RNA polymerase (RdRps). It has the characteristic of acting on RNA viruses including Ebola and Coronaviruses especially novel coronavirus (2019-nCoV). The purpose of this study is to evaluate the clinical efficacy and safety of Favipiravir in comparison to placebo in the treatment of mild COVID-19 cases. It is a Multicenter, randomized double-blinded, parallel-group trial.

Conditions

Interventions

TypeNameDescription
DRUGFavipiravir1800 mg twice daily for one day, followed by 800mg (4 tablets) twice daily
DRUGPlacebo(9 tablets) by mouth twice daily for one day, followed by (4 tablets) twice daily (Maximum days of therapy is 7 days)

Timeline

Start date
2020-07-23
Primary completion
2021-08-04
Completion
2021-08-04
First posted
2020-07-09
Last updated
2021-11-05

Locations

7 sites across 1 country: Saudi Arabia

Source: ClinicalTrials.gov record NCT04464408. Inclusion in this directory is not an endorsement.