NCT04463030

Antioxidant Bioavailability

Clinical Pilot Study on Antioxidant Uptake and Downstream Effects

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 24 (estimated)
• Sponsor: Natural Immune Systems Inc · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Accepted

Summary

A small cross-over trial on 3 different doses of liposomal vitamin C, comparing vitamin C uptake and downstream effects when 24 people consume 1, 2, and 5 grams on different test days, compared to placebo.

Detailed description

A randomized, cross-over study design will be used to evaluate the effects of consumption of 4 different doses of liposomal vitamin C (0, 1, 2, and 5 grams). The study is of 5 weeks' duration, with evaluation of a different dose at each of week 1, week 3 and week 5 with a one week washout between each dose.

Conditions

• Pharmacokinetics

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Liposomal vitamin C, 1 gram	after a blood draw 1 gram of vitamin c will be consumed followed by 3 additional blood draws
DIETARY_SUPPLEMENT	Liposomal vitamin C, 2 grams	after a blood draw 2 grams of vitamin c will be consumed followed by 3 additional blood draws
DIETARY_SUPPLEMENT	Liposomal vitamin C, 5 grams	after a blood draw 5 grams of vitamin c will be consumed followed by 3 additional blood draws
DIETARY_SUPPLEMENT	Placebo	after a blood draw placebo will be consumed followed by 3 additional blood draws

Timeline

• Start date: 2020-07-01
• Primary completion: 2022-12-25
• Completion: 2023-06-25
• First posted: 2020-07-09
• Last updated: 2022-09-27

Locations

1 site across 1 country: United States