Trials / Unknown
UnknownNCT04462978
Non-Immunoglobulin E-mediated Food Allergies in Children
Investigating Clinical Features, Natural Course and Pathophysiology of Non-Immunoglobulin E-mediated Food Allergies in the Pediatric Age
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 150 (estimated)
- Sponsor
- Federico II University · Academic / Other
- Sex
- All
- Age
- 1 Day – 14 Years
- Healthy volunteers
- Accepted
Summary
Non-IgE-mediated gastrointestinal food allergies (non-IgE-GIFA) are an evolving web of clinical conditions characterized by subacute and/or chronic symptoms and include food protein-induced enterocolitis syndrome (FPIES), food protein-induced enteropathy (FPE), food protein-induced allergic proctocolitis (FPIAP), and food protein-induced allergic dysmotility disorders (gastroesophageal reflux disease (GERD), colic and constipation) (FPIMD). Despite the prevalence and clinical impact of these conditions, the pathogenesis as well as the natural history and the best management of these disorders are still poorly defined. These limitations could be responsible for diagnostic delays and errors, and suboptimal clinical management. We aim to evaluate clinical features, natural course and pathophysiology of non-IgE-GIFA in the pediatric age.
Conditions
- Non IgE Mediated Food Allergy
- Food Protein-Induced Enteropathy
- Food Protein-Induced Proctocolitis
- Food Protein-Induced Enterocolitis Syndrome
- Food Protein-induced Motility Disorders
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Non IgE-mediated food allergy |
Timeline
- Start date
- 2017-01-01
- Primary completion
- 2023-12-30
- Completion
- 2025-12-28
- First posted
- 2020-07-08
- Last updated
- 2022-03-11
Locations
1 site across 1 country: Italy
Source: ClinicalTrials.gov record NCT04462978. Inclusion in this directory is not an endorsement.