Clinical Trials Directory

Trials / Completed

CompletedNCT04462315

10-Years Follow-up of the EXAMINATION Trial

Ten-year Follow-up of the Clinical Evaluation of Everolimus-Eluting Coronary Stents in the Treatment of Patients With ST-segment Elevation Myocardial Infarction: EXAMINATION-EXTEND Trial

Status
Completed
Phase
Study type
Observational
Enrollment
1,498 (actual)
Sponsor
Hospital Clinic of Barcelona · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The EXAMINATION trial was a superiority trial that compared everolimus-eluting stents (EES) versus bare-metal stents (BMS) in an all-comer ST-segment elevation myocardial infarction (STEMI) population. The patient-oriented endpoint was not superior at 1-year, but it was at 5-year. However, very-long term follow-up is unknown. The study had an independent Clinical event Committee (CEC). All events were adjudicated by an independent clinical committee, according to the Academic Research Consortium 1.

Conditions

Interventions

TypeNameDescription
DRUGEverolimus Eluting Coronary Stent SystemEverolimus Eluting Coronary Stent System (Everolimus Arm) implantation
DEVICECobalt chromium balloon expandable stent (non-drug-eluting stent Arm)Cobalt chromium balloon-expandable stent (non-drug-eluting stent Arm) implantation

Timeline

Start date
2015-05-01
Primary completion
2020-05-31
Completion
2020-05-31
First posted
2020-07-08
Last updated
2022-09-01

Locations

11 sites across 3 countries: Italy, Netherlands, Spain

Source: ClinicalTrials.gov record NCT04462315. Inclusion in this directory is not an endorsement.