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CompletedNCT04457011

Efficacy and Safety of Susu Zhike Granules for Treating Acute Cough Due to Common Cold With Cold-cough Syndrome in Children

The Efficacy and Safety Evaluation of Susu Xiao'er Zhike Granules in the Treatment of the Cough Caused by the Common Cold(Wind Cold Cough Syndromes) in Children: a Randomized, Double-blind, Dose Exploration,Multi-center Phase II Clinical Trial

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
240 (actual)
Sponsor
Tasly Pharmaceutical Group Co., Ltd · Industry
Sex
All
Age
6 Years – 14 Years
Healthy volunteers
Not accepted

Summary

This protocol is designed with the aim of exploring the efficacy of Susu on shortening duration and reducing severity of cough, and observe the safety used in children.

Detailed description

Susu used to be a clinical experienced Chinese herb formula for treating acute cough caused by common cold. The ingredients includes Hua Ju Hong, Qiao Rui Su, Zi Su Ye, Jie Geng, Gan Cao,which relieving cold and cough, resolving phlegm in traditional Chinese medicine theory. This prescription was used for a long time in clinical for treatingacute cough caused by common cold as an herb formula. To standardize the quality and make it easier to take, we reproduced it into a patent medicine and design this trial for evaluating it.

Conditions

Interventions

TypeNameDescription
DRUGHigh dose Susu Xiao'er Zhike Granules 1 bagHigh dose Susu Xiao'er Zhike Granules 1 bag(9g granule per bag,contains 20.25 g crude herbs), twice a day (7-9a.m. and 5-7p.m.) for five days
DRUGMiddle dose Susu Xiao'er Zhike Granules 1 bagMiddle dose Susu Xiao'er Zhike Granules 1 bag(9g granule per bag,contains 10.12 g crude herbs), twice a day (7-9a.m. and 5-7p.m.) for five days
DRUGExtremely-low dose Susu Xiao'er Zhike Granules 1 bagExtremely-low dose Susu Xiao'er Zhike Granules 1 bag(9g granule per bag,contains 1.01 g crude herbs), twice a day (7-9a.m. and 5-7p.m.) for five days

Timeline

Start date
2020-09-19
Primary completion
2022-02-24
Completion
2022-02-24
First posted
2020-07-07
Last updated
2024-09-05

Locations

7 sites across 1 country: China

Source: ClinicalTrials.gov record NCT04457011. Inclusion in this directory is not an endorsement.

Efficacy and Safety of Susu Zhike Granules for Treating Acute Cough Due to Common Cold With Cold-cough Syndrome in Child (NCT04457011) · Clinical Trials Directory