NCT04455295

Testing the Noradrenergic Hypothesis of Transcutaneous Vagus Nerve Stimulation

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 55 (estimated)
• Sponsor: Arkansas Tech University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

This study investigates the capacity of non-invasive vagus nerve stimulation, applied at the ear, to alter to measures of locus coeruleus output pupil diameter and EEG alpha power. Non-invasive alteration in locus coeruleus output is of interest in regard to basic science and has potential clinical implications in a number of conditions.

Conditions

• no Condition
• Electroencephalography
• Pupil Diameter

Interventions

Type	Name	Description
DEVICE	Transdermal Vagus Nerve Stimulation (tVNS)	Mild non-invasive transdermal electrical stimulation at the ear (0.0-1.0 mA, 0.0-30.0 Hz). Used in previous studies with no unexpected adverse events. Stimulator not considered a FDA regulated device in previous studies.

Timeline

• Start date: 2020-09-01
• Primary completion: 2025-06-01
• Completion: 2025-06-01
• First posted: 2020-07-02
• Last updated: 2024-02-28

Locations

1 site across 1 country: United States