NCT04451421

Effects of Standing at Different Angles on Transpulmonary Pressure

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 50 (estimated)
• Sponsor: Chinese PLA General Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 95 Years
• Healthy volunteers: Not accepted

Summary

Effects of standing at different angles on transpulmonary pressure

Detailed description

Objective: To study the effect of different standing angles on cross-lung pressure.Background: Long-term bed rest in ICU patients leads to upward movement of diaphragm and increased intrathoracic pressure in mechanically ventilated patients, resulting in lower cross-lung pressure. If the end-expiratory cross-lung pressure is negative, lung tissue compression and atelectasis will occur.Standing can lower the diaphragm, improve the pressure across the lungs, and improve ventilation.Selection methods: patients with invasive mechanical ventilation in the ICU, on the premise of stable hemodynamics, with the aid of electric bed training in standing in different angles, start from 20 degrees, 5 degrees up every five minutes, the largest up to 80 degrees, each Angle across the pulmonary pressure, die cavity ratio, tidal volume and breathe out carbon dioxide at the end of the record, and record whether low blood pressure, an accident in the process of take off the tube and other adverse reactions.

Conditions

• Pulmonary Disease

Interventions

Type	Name	Description
BEHAVIORAL	Change of standing Angle	Change the patient's standing Angle by using an electric bed

Timeline

• Start date: 2020-10-01
• Primary completion: 2021-10-01
• Completion: 2021-10-01
• First posted: 2020-06-30
• Last updated: 2020-07-07