NCT04451148

Gut Microbiome and Obesity

Gut Microbiome As Target of Intervention Against Obesity and Metabolic Syndrome

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 120 (estimated)
• Sponsor: Federico II University · Academic / Other
• Sex: All
• Age: 10 Years – 16 Years
• Healthy volunteers: —

Summary

Pediatric obesity is a risk factor for the onset of obesity in adulthood and is a risk factor for various chronic non-communicable diseases. Metabolic syndrome (MS) is the name for a group of risk factors that increase cardiovascular risk and other health problems characterized by the presence of abdominal obesity, dyslipidemia, hyperglycaemia and high blood pressure. Numerous preclinical and clinical data suggest a potential role of the intestinal microbiota in these diseaes. Unfortunately, comparative studies of the gut microbiota are still scarce in pediatric subjects suffering from obesity than obesity complicated by MS. The aim is to study the metagenomics and metabolomics characteristics of the intestinal microbiota in obese children/adolescents with or without MS, that could provide useful data for innovative intervention strategies for these conditions.

Conditions

• Obesity, Childhood
• Metabolic Syndrome

Interventions

Type	Name	Description
OTHER	Obese with or without metabolic syndromesubjects	Children with obesity and with or without metabolic syndrome

Timeline

• Start date: 2020-05-01
• Primary completion: 2022-05-01
• Completion: 2022-05-01
• First posted: 2020-06-30
• Last updated: 2020-07-07

Locations

1 site across 1 country: Italy