NCT04449718

Vitamin D Supplementation in Patients With COVID-19

Vitamin D Supplementation in Patients With COVID-19: A Randomized, Double-blind, Placebo-controlled Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 240 (actual)
• Sponsor: University of Sao Paulo · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Coronavirus disease 2019 (COVID-19) was declared an emergency public health problem by the World Health Organization (WHO) in March 2020. Since then, several initiatives by the medical and scientific community have sought alternatives to treat infected individuals, as well as identifying risk or protective factors for the contamination and prognosis of patients. In this perspective, vitamin D supplementation can improve some important outcomes in critically ill patients, being considered a potent immunomodulatory agent. Vitamin D deficiency is a common outcome in critically ill patients, thus making it a modifiable risk factor with great potential for reducing hospital stay and intensive care and mortality. The investigators speculate that vitamin D supplementation could have therapeutic effects in patients with COVID-19.

Conditions

• COVID-19

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Vitamin D	200,000 IU on admission
DIETARY_SUPPLEMENT	Placebo	200,000 IU on admission

Timeline

• Start date: 2020-06-01
• Primary completion: 2020-10-07
• Completion: 2020-10-07
• First posted: 2020-06-29
• Last updated: 2020-11-17

Locations

1 site across 1 country: Brazil