Trials / Completed
CompletedNCT04448821
A Clinical Trial to Evaluate the Effect of Nilotinib on the PK/PD of Meformin
A Clinical Trial to Evaluate the Effect of Nilotinib on the Pharmacokinetics and Pharmacodynamics of Metformin in Healthy Male Adults
- Status
- Completed
- Phase
- Phase 1
- Study type
- Interventional
- Enrollment
- 16 (actual)
- Sponsor
- Hyewon Chung · Academic / Other
- Sex
- Male
- Age
- 19 Years – 50 Years
- Healthy volunteers
- Accepted
Summary
The aim of the study is to evaluate the effect of nilotinib on the pharmacokinetics and pharmacodynamics of metformin in healthy male adults
Detailed description
Pharmacokinetics and pharmacodynamics of metformin without coadministration of nilotinib will be compared with those after administration of nilotinib.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Metformin | Single administration of metformin |
| DRUG | Metformin + Nilotinib | Coadministration of metformin and nilotinib |
Timeline
- Start date
- 2020-07-23
- Primary completion
- 2020-09-07
- Completion
- 2020-09-07
- First posted
- 2020-06-26
- Last updated
- 2020-11-04
Locations
1 site across 1 country: South Korea
Source: ClinicalTrials.gov record NCT04448821. Inclusion in this directory is not an endorsement.