NCT04448730

Polycystic Ovary Syndrome and BETATROPHIN

Can the Betatrophin be a Reliable Marker of Insulin Resistance in Normal Weight and Overweight Women With Polycystic Ovary Syndrome?

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 73 (actual)
• Sponsor: Hatice Akkaya · Other Government
• Sex: Female
• Age: 18 Years – 40 Years
• Healthy volunteers: Not accepted

Summary

This is an original study giving an information about the association body mass index, polycystic ovary syndrome and betatrophin.

Detailed description

Introduction: Betatrophin is a protein hormone which has a significant role in glucose homeostasis and lipid metabolism. The aim of this study is to compare the levels of serum betatrophin in overweight and normal weight women with PCOS. Material and Method: Thirty-five patients normal weight women with PCOS (BMI\<25) and 38 obese women with PCOS (BMI≥25) were included in this prospective, cross-sectional study. Patients were selected according to Rotterdam criteria. Serum betatrophin levels were studied by ELISA method and then compared between these two groups besides the following additional parameters as waist circumference/hip circumference ratio, fasting blood glucose, 75 g OGTT (oral glucose tolerance test) results and HOMA-IR levels.

Conditions

• Polycystic Ovary
• Obesity

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	serum marker levels	two groups comparisons

Timeline

• Start date: 2018-01-01
• Primary completion: 2019-07-30
• Completion: 2019-12-30
• First posted: 2020-06-26
• Last updated: 2020-06-26

Locations

1 site across 1 country: Turkey (Türkiye)