NCT04447391

Effects of a 12-week Combined Exercise Program on Ghrelins in Obese Adolescent Girls

Effects of a 12-week Combined Exercise Program on Acylated and Desacyl Ghrelin, and Ghrelin O Acyl Transferase in Obese Adolescent Girls

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (actual)
• Sponsor: Pusan National University Yangsan Hospital · Academic / Other
• Sex: Female
• Age: 16 Years – 18 Years
• Healthy volunteers: Accepted

Summary

This study aimed to explore the effects of a 12-week combined exercise on ghrelin O acyl transferase, acylated ghrelin and desacylated ghrelin levels in obese girls.

Detailed description

Little is known about on ghrelin O acyl transferase (GOAT), acylated ghrelin (AG) and desacylated ghrelin (DAG) levels during long-term exercise in adolescent population. Our previous study showed that combined exercise program in overweight children increases DAG with unchanged AG. This study aimed to explore the effects of a 12-week combined exercise on GOAT, AG, and DAG in obese girls.

Conditions

• Ghrelin

Interventions

Type	Name	Description
OTHER	Combined exercise program	Combined exercise programme, consisting of warm-up, aerobic exercise, resistance training, and cool-down, 3 days a week after school for 50 minutes from 17;30 under supervision by a trainer plus 300 kcal deficit diet
OTHER	Control	300 kcal deficit diet only

Timeline

• Start date: 2015-09-10
• Primary completion: 2015-12-30
• Completion: 2015-12-31
• First posted: 2020-06-25
• Last updated: 2020-06-26

Locations

1 site across 1 country: South Korea