NCT04447222

Impact of the COVID-19 Pandemic and HRQOL in Cancer Patients and Survivors

COVID-19: Well-Being and HRQOL in Cancer Patients Who Participated in Prior Behavioral Clinical Trials

• Status: Active Not Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 1,242 (estimated)
• Sponsor: M.D. Anderson Cancer Center · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Accepted

Summary

This study uses questionnaires to gain an understanding of how experiences during the COVID-19 pandemic, regardless of COVID-19 status, may have impacted health-related quality of life (HRQOL) and other areas such as COVID-19-specific psychological distress, disruptions to health care, finances and social interactions in cancer patients. The coronavirus disease 2019 (COVID-19) is an infectious disease that is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The information learned from this study will guide the development of psychosocial programs to improve patient care and outcomes in cancer patients and survivors in the context of facing a global pandemic.

Detailed description

PRIMARY OBJECTIVES: I. Assess experiences during the coronavirus disease-2019 (COVID-19) pandemic (e.g., exposure, risk factors, testing, isolation, seropositivity, hospitalization, loss of family or friends); COVID-19-specific psychological distress (e.g., fear, anxiety and depressive symptoms); health, financial and social disruptions; perceived benefits and social support; and HRQoL and other psychosocial and behavioral factors in cancer survivors who participated in one of three prior clinical trials. II. Evaluate the extent to which COVID-19 experiences are associated with COVID-19 specific psychological distress, health, financial and social disruptions, perceived benefits and social support, and HRQoL. III. Evaluate the extent to which resiliency factors such as social support and perceived benefits assessed concurrently and other psychosocial measures assessed in the prior trials moderate the effects of COVID-19 experiences on COVID-19-specific psychological distress and HRQoL. IV. Examine group differences in the outcomes assessed in the protocol relative to prior group assignment in the behavioral clinical trials. OUTLINE: Participants complete a survey online over 35-45 minutes about their experiences regarding the COVID-19 pandemic.

Conditions

• COVID-19 Infection
• Malignant Solid Neoplasm

Interventions

Type	Name	Description
OTHER	Quality-of-Life Assessment	Ancillary studies
OTHER	Questionnaire Administration	Ancillary studies
OTHER	Survey Administration	Complete survey

Timeline

• Start date: 2020-05-12
• Primary completion: 2026-07-30
• Completion: 2026-07-30
• First posted: 2020-06-25
• Last updated: 2026-02-19

Locations

1 site across 1 country: United States