Trials / Recruiting
RecruitingNCT04443439
Assess the Risk of Cerebrovascular Disease
Head and Neck CTA Combined With Multimodal MRI to Assess the Risk of Cerebrovascular Disease
- Status
- Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 100 (estimated)
- Sponsor
- Tang-Du Hospital · Academic / Other
- Sex
- All
- Age
- —
- Healthy volunteers
- Not accepted
Summary
Intracranial artery stenosis is an important cause of ischemic stroke, but the degree of intracranial artery stenosis is not completely matched with the symptoms of ischemic stroke. Asymptomatic carotid stenosis (ACS) refers to does not appear related neurological symptoms of carotid stenosis and stroke or transient ischemic attack of carotid stenosis, did not happen cerebrovascular events such as stroke, but there have been a different degree of cognitive impairment, be badly in need of development of noninvasive imaging methods, objective evaluation of the ACS group cognitive impairment, and predict the ACS risk of ischemic stroke. Therefore, this topic proposed comprehensive cognitive assessment, CTA, double modal MRI techniques, clinical and biochemical indicator detection, mathematical modeling and statistical analysis techniques, assess the ACS group and normal person the cognitive ability, the difference of NVC and local perfusion, and follow-up ACS crowd of ischemic stroke and other cardiovascular events, discuss ACS and cognitive impairment, the correlation of NVC and local perfusion abnormalities, screening of radiographic predictor of ischemic stroke, and in the follow-up of ACS population in testing the sensitivity of the series of indicators and specific degrees.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DEVICE | GE Discovery MR750 3.0t superconducting MRI | T2WI, FLAIR, DWI, 3D BRAVO, 3D-ASL, rs-fMRI, DKI sequences to exclude other organic lesions |
Timeline
- Start date
- 2020-10-09
- Primary completion
- 2026-11-15
- Completion
- 2026-12-01
- First posted
- 2020-06-23
- Last updated
- 2022-10-25
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT04443439. Inclusion in this directory is not an endorsement.