Trials / Completed
CompletedNCT04443231
Prospective Clinical Study of Retinal Microvascular Alteration After ICL Implantation
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 25 (actual)
- Sponsor
- Peking University Third Hospital · Academic / Other
- Sex
- All
- Age
- 18 Years – 45 Years
- Healthy volunteers
- Accepted
Summary
To observe the retinal microvascular alteration during 3 months follow-up after Implantable Collamer Lens (ICL) operation in moderate and high myopia patients using quantitative optical coherence tomography angiography (OCTA) analysis.
Detailed description
The study object is moderate and high myopia patients, underwent ICL implantation. OCTA was used to image the superficial and deep retinal vascular plexuses before ICL implantation surgery and at 3 months follow-up. OCTA images were corrected for magnification, skeletonized, separated the large vessels and partitioned. Retinal microvascular density was measured by using fractal dimension analysis. The aim of this study was to uncover potential retinal vascular network alterations induced by ICL implantation surgery.
Conditions
- Adolescent
- Adult
- Human
- Male
- Female
- Follow-up Studies
- Prospective Studies
- Lens Implantation, Intraocular
- Myopia
- Phakic Intraocular Lenses
- Retinal Vessels
- Postoperative Period
- Preoperative Period
- Tomography, Optical Coherence
Interventions
| Type | Name | Description |
|---|---|---|
| DEVICE | Optical Coherence Tomography Angiography | AngioVue (Optovue, Fremont, CA, USA) was used to capture the OCTA images before ICL surgery and at 3 months follow-up. |
Timeline
- Start date
- 2018-11-01
- Primary completion
- 2019-10-01
- Completion
- 2019-10-01
- First posted
- 2020-06-23
- Last updated
- 2020-06-23
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT04443231. Inclusion in this directory is not an endorsement.