NCT04442906

Analgesia After Knee Arthroscopy :Dexmedetomidine vs Fentanyl

Comparative Study Between Dexmedetomidine and Fentanyl as an Adjuvant to Intra-articular Bupivacaine for Postoperative Analgesia After Knee Arthroscopy.

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 45 (actual)
• Sponsor: Zagazig University · Other Government
• Sex: All
• Age: 21 Years – 45 Years
• Healthy volunteers: Accepted

Summary

The aim of this study is to evaluate analgesic effects Bupivacaine, Bupivacaine plus Dexmedetomidine and Bupivacaine plus Fentanyl in relieving pain after knee arthroscopic surgery.

Detailed description

Forty-five patients ASA I - II aged 21-45 years for elective knee arthroscopy were divided into 3 groups: Group B, BD and BF. Group B received Intra-articular injection of 20 ml bupivacaine 0.25%+ 1 ml saline. Group BD received Intra-articular injection of 20 ml bupivacaine 0.25%+ 1 ml dexmedetomidine (100 ug). Group BF received Intra-articular injection of 20 ml bupivacaine 0.25%+ 1 fentanyl (50 ug). The time of first request of analgesia and analgesic effect by VAS during the first 24 hr. postoperatively are recorded.

Conditions

• Analgesia

Interventions

Type	Name	Description
DRUG	Dexmedetomidine	Group BD received Intra-articular injection of 20 ml bupivacaine 0.25%+ 1 ml dexmedetomidine (100 ug).
DRUG	Fentanyl	Group BF received Intra-articular injection of 20 ml bupivacaine 0.25%+ 1 fentanyl (50 ug)
DRUG	Bupivacain	Group B received Intra-articular injection of 20 ml bupivacaine 0.25%+ 1 ml saline.

Timeline

• Start date: 2020-07-01
• Primary completion: 2020-11-01
• Completion: 2020-12-01
• First posted: 2020-06-23
• Last updated: 2021-01-25

Locations

1 site across 1 country: Egypt