NCT04440397

Relationship Between Endoplasmic Reticulum Stress and Pain in Patients With Endometriosis

Endoplasmic Reticulum Stress and Endometriosis Releated Pain

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 86 (actual)
• Sponsor: Kanuni Sultan Suleyman Training and Research Hospital · Academic / Other
• Sex: Female
• Age: 18 Years – 50 Years
• Healthy volunteers: Accepted

Summary

The correlation between painful symptoms (dysmenorrhea, dysparonia, dysuria, chronic pelvic pain) symptoms and endoplasmic reticulum stress was investigated in 86 patients diagnosed with endometriosis. For this, xbp-1 (x box binding protein-1) level was measured in patients. XBP-1 is an endoplasmic reticulum stress indicator and is known to be involved in pain pathogenesis.

Detailed description

Women between the ages of 18-50 who were diagnosed with endometriosis by surgery and ultrasound, without known rheumatological or metabolic diseases were included in the study. Most of the patients are composed of newly diagnosed patients.

Conditions

• Endometriosis
• Endoplasmic Reticulum Stress
• Endometriosis-related Pain

Interventions

Type	Name	Description
OTHER	xbp-1 - endometriosis patients group	Patients diagnosed with endometriosis by surgery and ultrasound and whose xbp-1 level was examined

Timeline

• Start date: 2020-03-17
• Primary completion: 2020-08-01
• Completion: 2020-08-04
• First posted: 2020-06-19
• Last updated: 2020-08-07

Locations

1 site across 1 country: Turkey (Türkiye)