NCT04432610

Echocardiographic Study of a Single Dose Bisoprolol Versus Nebivolol in Healthy Subjects

Echocardiographic Study of a Single Dose Bisoprolol Versus Nebivolol in Healthy Subjects: a Randomized, Double-blind, Cross-over Study

• Status: Withdrawn
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: Clinical Hospital Center Zemun · Academic / Other
• Sex: All
• Age: 20 Years – 60 Years
• Healthy volunteers: Accepted

Summary

This is a randomized, double-blind, crossover study in healthy adult subjects. Each subject will receive a single dose of bisoprolol 5 mg p.o. and nebivolol 5 mg p.o. with 1 week washout period. All subjects will undergo a physical examination, 12-lead electrocardiography and a comprehensive echocardiographic study before the administration of the study drug and 5 hours thereafter.

Conditions

• Bisoprolol Adverse Reaction
• Nebivolol Adverse Reaction

Interventions

Type	Name	Description
DRUG	Bisoprolol versus Nebivolol	All subjects will receive both drugs, but at different time periods determined by randomization, with 1 week washout period

Timeline

• Start date: 2030-01-01
• Primary completion: 2030-12-01
• Completion: 2030-12-01
• First posted: 2020-06-16
• Last updated: 2022-12-20

Locations

1 site across 1 country: Serbia