NCT04432467

Fertility Restoration Using Autologous Mesenchymal Stem Cells

Fertility Restoration Using Autologous Adipose Tissue Derived Mesenchymal Stem Cells

• Status: Completed
• Phase: Phase 1 / Phase 2
• Study type: Interventional
• Enrollment: 10 (actual)
• Sponsor: Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus · Other Government
• Sex: Female
• Age: 18 Years – 45 Years
• Healthy volunteers: Not accepted

Summary

Treatment of the patients with scarring and adhesions in the uterus resulting from caesarean section or chronic inflammation in the mucosa of the uterus and fallopian tubes and preventing the occurrence of these effects in the future

Detailed description

The aim of the project is to develop a biomedical cell product based on autologous adipose tissue derived mesenchymal stem cells and a biodegradable carrier for highly effective treatment and prevention of scarring and adhesions in the uterus acquired as a result of cesarean section or chronic inflammatory processes in the uterine mucosa and fallopian tubes; to conduct the clinical trials of the biomedical cell product in the treatment of uterus scarring and infertility in women.

Conditions

• Chronic Endometritis
• Uterus; Scar
• Uterine Synechiae
• Fallopian Tube Obstruction

Interventions

Type	Name	Description
BIOLOGICAL	Autologous mesenchymal stem cells	Autologous adipose tissue-derived mesenchymal stem cells
OTHER	standard treatment	standard treatment according to clinical protocols

Timeline

• Start date: 2020-10-01
• Primary completion: 2021-09-30
• Completion: 2021-09-30
• First posted: 2020-06-16
• Last updated: 2021-12-10

Locations

1 site across 1 country: Belarus