Clinical Trials Directory

Trials / Completed

CompletedNCT04432324

Study to Evaluate the Safety and Efficacy of High Dose IVIG in Hospitalized Participants With Coronavirus Disease (COVID-19)

A Multicenter, Randomized, Open-label Parallel Group Pilot Study to Evaluate Safety and Efficacy of High Dose Intravenous Immune Globulin (IVIG) Plus Standard Medical Treatment (SMT) Versus SMT Alone in Hospitalized Subjects With COVID-19

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
100 (actual)
Sponsor
Instituto Grifols, S.A. · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of the study is to determine if high dose Intravenous IVIG plus SMT can reduce the proportion of participants dying or requiring intensive care unit (ICU) admission on or before Day 29 or who are dependent on high flow oxygen devices or invasive mechanical ventilation on Day 29 versus SMT alone in hospitalized participants with COVID-19.

Conditions

Interventions

TypeNameDescription
BIOLOGICALIntravenous Immune GlobulinIVIG Intravenous infusion
DRUGStandard Medical TreatmentSMT

Timeline

Start date
2020-06-02
Primary completion
2021-03-03
Completion
2021-03-03
First posted
2020-06-16
Last updated
2021-03-10

Locations

10 sites across 1 country: Spain

Source: ClinicalTrials.gov record NCT04432324. Inclusion in this directory is not an endorsement.